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Read now Fibrosis Fibrosis is a buildup of certain types of protein in the liver, including collagen. It features in most types of chronic liver disease.
Mild-to-moderate forms of fibrosis may be reversible. Continuous fibrosis and inflammation can lead to liver cancer. Cirrhosis Cirrhosis occurs when the liver has been inflamed for a long time, leading to scarring and loss of function.
This can be a life-threatening condition.
Cirrhosis damage is irreversible, but the patient can prevent further damage by continuing to avoid alcohol. Life-long abstinence can improve liver function, but the permanent and severe damage from cirrhosis might mean that the patient needs a liver transplant to survive.
As the liver no longer processes toxins properly, it will be more sensitive to medications and alcohol. Alcohol use speeds up the destruction of the liver, along with reducing the liver's ability to compensate for the current damage.
Risk factors Women face a higher risk of alcoholic liver disease, as they metabolize alcohol more slowly.
A number of factors increase the risk of alcoholic liver disease. People who drink beer and liquor may be more likely to experience liver disease, when compared with those who consume other alcoholic beverages, such as wine.
According to the American College of Gastroenterology, women who consume more than two drinks a day and men who consume more than three drinks a day for more than five years are at an increased risk for alcoholic liver disease. Women metabolize alcohol more slowly than men.
They also are more likely to quickly develop fibrosis, inflammation, and liver injury as a result of alcohol. Research has shown that women are more susceptible to the negative effects of alcohol compared to men, even at the same levels of alcohol intake.
Women who consume high amounts of alcohol and also carry excess body weight have a greater chance of developing chronic liver disease. However, obesity is also a risk factor for men.
Having hepatitis C increases the risk, and a person who consumes alcohol regularly and has had any type of hepatitis faces a higher chance of developing liver disease.
Hepatitis C also increases the risk of developing liver cancer. Genetic changes can affect the risk. If a person experience changes in the genetic profiles of particular enzymes that are key to alcohol metabolism, such as ADH, ALDH, and CYPE1, they will have a higher chance of developing alcoholic liver disease.
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Causes Not all heavy regular drinkers develop liver damage. It is not known why alcoholic liver disease affects some people and not others.
Acetaldehyde is a toxic chemical that is produced by the body's break down of alcohol. It damages the liver and leads to liver scarring and inflammation. This chemical appears to affect some people more than others.NERVOUS SYSTEM DISEASE Ed Friedlander, M.D., Pathologist [email protected] No texting or chat messages, please.
Ordinary e-mails are welcome. Addiction- a primary, chronic, neurobiologic disease, with genetic, psychosocial, and environmental factors influencing its development and manifestations. It is characterized by behaviors that include one or more of the following: impaired control over drug use, .
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Alcoholic liver disease is a result of overconsuming alcohol that damages the liver, leading to a buildup of fats, inflammation, and scarring.